To set up your Ledger hardware wallet, visit ledger.com/start. Begin by selecting your device model (Ledger Nano S or Ledger Nano X). Follow the on-screen instructions to connect your device to your computer or smartphone. You will be prompted to install the Ledger Live app, which is essential for managing your cryptocurrency. Next, initialize your device by creating a new wallet or recovering an existing one. Set up a secure PIN and write down your recovery phrase, storing it safely offline. Finally, confirm your setup and start managing your crypto assets with Ledger Live.